background: previous studies have demonstrated the value of serum procalcitonin (pct) as a marker of bacterial infection, as well as the rapid decrease in its concentration with appropriate antibiotic treatment. the aim of this study was to determine the variation in serum pct levels over time during the treatment of acute bacterial meningitis (abm) in adults. methods: in this prospective analy...

• antibodies to C. pneumoniae in the cerebrospinal fluid of patients with the disease [(1.) Yao, S., Stratton, C.W., Mitchell, W.M., Sriram, S. (2001). CSF oligoclonal bands in multiple sclerosis represent antibodies against Chlamydophila. Neurology 56, 1168-76. (2.) Fainardi, E., Castellazzi, M., Casetta, I. et al. (2004). Intrathecal production of Chlamydia pneumoniaespecific high-affinity an...

microorganisms play a major role in initiation and perpetuation of pulpal and periapical diseases. therefore, elimination of the microorganisms present in the root canal system is the fundamental objective of endodontic treatment. the use of mechanical debridement, chemical irrigation or other antimicrobial protocols and intra-canal medicaments are critical to attain this goal. the aim of this ...

The increasing presence of drug-resistant bacterial infections among hospitalAbstract ised patients has resulted in greater numbers of patients receiving inappropriate antimicrobial treatment. This has led to the development of a novel paradigm guiding the administration of empirical antimicrobial therapy for patients with serious infections in the hospital setting. Antibacterial de-escalation ...

We determined the prevalence of plasmid-mediated quinolone resistance mechanisms among non-Typhi Salmonella spp. isolated from humans, food animals, and retail meat in the United States in 2007. Six isolates collected from humans harbored aac(6')Ib-cr or a qnr gene. Most prevalent was qnrS1. No animal or retail meat isolates harbored a plasmid-mediated mechanism.

The pharmacokinetics of the quinolone enoxacin were studied after a 600-mg oral dose was given to each of six male volunteers. The levels of the compound were measured in serum, blister fluid, and urine. Absorption was variable, with peak levels (mean, 3.7 micrograms/ml) being attained between 0.75 and 3.0 h (mean, 1.9 h). The serum elimination half-life was 6.2 h, and 71.6% of the drug was rec...

Topical antibacterial agents occupy an important niche of antimicrobial therapy for both inpatients and outpatients. These agents, including antiseptic and antibiotic preparations, are used for prophylaxis and treatment of infection. Prophylactic uses include application for traumatic and surgical wounds, burns, intravascular catheters, and eradication of S. aureus nasal carriage. Topical antib...

Photocatalysis induced by TiO2 and UV light constitutes a decontamination and antibacterial strategy utilized in many applications including self-cleaning environmental surfaces, water and air treatment. The present work reveals that antibacterial effects induced by photocatalysis can be maintained even after the cessation of UV irradiation. We show that resin-based composites containing 20% Ti...

Treatment of clinical isolates of human pathogenic bacteria, which were known to be resistant to multiple commonly-used antibiotics, with refined leukocyte extracts from the American alligator (Alligator mississippiensis) resulted in a timeand concentration-dependent inhibition of bacterial proliferation. The alligator leukocyte extract exhibited the strongest antibacterial effect on Pseudomona...